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==Rhodiola Rosea== * "Rhodiola can work within 30 minutes of administration and continue for at least 4-6 hours." "[https://brainalia.com/resources/nootropics-for-motivation/ Its chemical pathway provides the same effect as L-Tyrosine, but it starts working on the opposite side of the spectrum. Instead of promoting synthesis of dopamine, it regulates the activity of cortisol, the stress hormone, also known as the motivation killer.]" "[https://www.reddit.com/r/Nootropics/comments/89e8by/high_dose_rhodiola_rosea_zen_focus/dwqu3kx/ Diminishing returns apply here as with most things, tolerance or something like it definitely builds up. I would not rely on high-dose rhodiola as a performance enhancer in the way you would use a stimulant]. Rhodiola is my fave supplement of all time, have been using it for over 10 years, but I guarantee that the effects diminish and you'll have to cycle off it eventually. Once your body adjusts to the dosage, I'm betting that a high dose like that is going to just give you major anxiety and jitters. Definitely happens to me. When I'm using Rhodiola, I usually take a low dose, and take a higher dosage only if I'm really adrenally wrecked, sleep deprived, tired, hungover, etc. If you want to dose twice a day, one in the early morning and one before lunch is a good schedule, otherwise you may be overstimulated in the evening." Brands: "I always feel like NOW has such varying quality. I usually have more success with Source Natural and Thorne. Right now I have Thorne Rhodiola and effects are noticeable." "[https://nootrodelic.com/ashwagandha-vs-rhodiola-vs-ginseng-vs-holy-basil/#Ashwagandha_vs_Rhodiola Ashwagandha combined with Rhodiola can cancel each other out, as one is sedating while the other produces mild stimulation.]" "[https://www.reddit.com/r/Nootropics/comments/cbm2s6/rhodiola_is_the_best_antid_ive_ever_tried_whats/etic6uu/ showing that it only increases BDNF for something like 7 days, then it actually lowers it below baseline. So it would seem the catch is that it doesn't work for long and needs to be cycled at minimum]" [https://www.youtube.com/watch?v=gHLZhR4KUI8 Do not take with '''MAOI''']. "[https://nootropicsexpert.com/rhodiola-rosea/ MAOI meds influence serotonin levels in the brain. So taking MAOIβs in combination with Rhodiola Rosea has the potential to cause serotonin syndrome.]" [https://www.aliem.com/serotonin-syndrome-older-patient-altered-mental-status/ "'''quetiapine (Seroquel)''' has serotonin 5-HT2 antagonist properties, but paradoxically has been reported to enhance the serotonergic effect of other serotonin modulators and '''contribute to serotonin syndrome'''"]
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